Stereotactic vacuum-assisted breast biopsy: our experience and comparison with stereotactic automated needle biopsy.

OBJECTIVES To evaluate and compare the outcome of stereotactically guided percutaneous, directional, vacuum-assisted breast biopsy (VAB) with the outcome of those performed with 14-gauge automated gun. METHODS Between January 2008 and January 2011, altogether 257 stereotactic biopsies were performed in our institute; 193 with the 14-gauge automated needle and 64 with a directional, vacuum-assisted instrument. Patients with malignant or high risk lesions were encouraged to undergo an excisional biopsy. We evaluated and compared concordance between the biopsy results and subsequent examinations (surgical excision or follow up) for both methods. RESULTS VAB demonstrated 57 (89 %) benign lesions, 2 (3 %) high risk and 5 (8 %) malignant lesions. We obtained post-bioptic mammographic or histological evaluation for altogether 51 lesions, with one (12.5 %) false negative case, one case of underestimation of borderline lesion, and no false positive cases. Clusters of microcalcifiation were completely removed in 18 lesions (28 %). CONCLUSION Vacuum-assisted biopsy outperformed the 14-gauge automated needle biopsy with a lower disease underestimation, sensitivity and false-negative rates; however these differences were not statistically significant due to small data files and relatively small number of identified malignant lesions in the vacuum-assisted biopsy group.VAB completely removed significantly more clusters of microcalcifications in comparison to the automated needle biopsy, which significantly reduced the need for surgery in benign lesions (Tab. 7, Fig. 3, Ref. 32).